In childhood annual dental screening should start at about 8 years of age. Screening should continue into adult life. However, the frequency will depend on the findings of each X-ray or MRI. To ensure effective management of jaw cysts they … Continue reading →
A fibroma is a solid benign lump on the ovary. Calcium can also build up on the ovary. Studies show that 20% – 25% of women with Gorlin syndrome have ovarian fibromas and/or calcification (a build up of calcium). They cause … Continue reading →
In some patients with Gorlin Syndrome radiotherapy may lead to the rapid development of new basal cell carcinomas and therefore should be used under special / exceptional circumstances. … Continue reading →
Mohs surgery is a precise surgical technique used to treat skin cancer. During Mohs surgery, thin layers of cancer-containing skin are removed and examined until only cancer-free tissue remains. Mohs surgery is also known as Mohs micrographicsurgery. … Continue reading →
Counselling is not commonly offered on diagnosis or even later on. If you feel you need help in coming to terms with Gorlin Syndrome speak to your GP or Consultant. … Continue reading →
The Gorlin Syndrome Group is a support network offering guidance and information to individuals with Gorlin Syndrome, and their families and carers. The group is organised by people with the condition and their families. We are supported by a medical … Continue reading →
PellePharm presents updated data from Phase 2 Studies demonstrating the potential of Patidegib Topical Gel to treat Basal Cell Carcinomas in patients with Gorlin Syndrome and in patients with non-Gorlin sporadic BCCs. PellePharm, a late clinical-stage biopharmaceutical company committed to targeting … Continue reading →
Gorlin Syndrome is an autosomal dominant genetic condition which can affect either sex. The Gorlin gene is one of approximately 100,000 genes present in each one of our cells (the body’s building blocks). For every characteristic humans possess, we inherit … Continue reading →
In the diagram below, the two chromosomes of each parent are shown. The gene for Gorlin syndrome with the faulty gene is coloured in red, the “normal” genes in white. Each child with the syndrome inherits either the faulty or … Continue reading →
Few studies of Gorlin syndrome prevalence exist. The most quoted prevalence figure 1:57,000 comes from a study of a UK population of four million in North West England (Evan at el. Journal of Medical Genetics 1993). Since publication of the study, an … Continue reading →
