Clinical Commissioning Policy: Vismodegib

Clinical commissioning policy Vismodegib is recommend to be available as a treatment option through routine commissioning for adults with either Gorlin syndrome or non-Gorlin syndrome related multiple basal cell carcinomas within the criteria set out The use of...

Itraconazole and Gorlin Syndrome.

Drugs, such as Vismodegib, are often only partly or temporarily helpful in Gorlin SyndromeItraconazole has been used for many years to treat fungal infections. For this reason, Itraconazole is cheap and we know about the side effects. Test tube experiments show...

Vismodegib in the UK

Why isn’t vismodegib recommended in the UK? Vismodegib (also known as Erivedge) is a medication shown to have some benefits in basal cell cancer. It’s taken by mouth and is the first ‘hedgehog pathway inhibitor’ to be licensed for use. After it was licensed in...

NICE Guidance – Skin Tumours including Melanoma

The NICE clinical guidelines on skin tumours outlines how healthcare services for people with skin tumours should be organised. The guidance published in February 2006 and updated May 2010 indicates that ‘protocols should cover the management of care for people...

Treatment Priorities

To ensure effective management of Gorlin syndrome it is vital that individuals are treated in the early stages and for this reason regular surveillance is recommended. Basal Cell Carcinomas 90% of individuals with Gorlin Syndrome will develop basal cell carcinomas at...