To ensure effective management of Gorlin syndrome it is vital that individuals are treated in the early stages and for this reason regular surveillance is recommended.
Basal Cell Carcinomas
90% of individuals with Gorlin Syndrome will develop basal cell carcinomas at some stage in their life.
It is vital that individuals are treated in the early stages and for this reason regular surveillance is recommended to ensure:
- Prompt treatment for best cosmetic effects
- Eradication of aggressive basal cell carcinomas
- Particular attention to individual lesions occurring around the eyes, nose, mouth and ears
- Preservation of normal tissue to prevent disfigurement
It is highly recommended that individuals with Gorlin Syndrome are seen on a regular basis by an experienced Dermatologist.
Preservation of ovarian tissue whenever ovarian fibromas require surgical treatment.
Radiotherapy is to be avoided unless other therapies are unavailable and the use of diagnostic X-rays should be used sparingly. It is essential that individuals protect themselves from the sun by the use of a complete sun block and by covering exposed skin with long sleeves, high collars and hats.
Ref: Neviod Basal Cell Carcinoma Syndrome. Synonyms: Basal Cell Nevus syndrome (BCNS), Gorlin syndrome, NBCCS. D Gareth Evans, MD, FRCP and Peter A Farndon, MD, FRCP Gene Reviews 20301330 Oct 2015
To see full article see Gene Reviews
Reviewed and verified by Medical Advisers in conjunction with the Gorlin Syndrome Group 02/04/2018. Next Review April 2019.