They are solid benign lumps on the ovary which often become calcified. 25% – 30% of Gorlin women are affected by ovarian fibroma and/or calcification. They cause no problems unless they are large.
No hard and fast rule. In some people they do slow down with age, in others there is little difference.
Photodynamic therapy (PDT) is a promising non-surgical technique that involves the systemic or topical application of a photosensitising drug that is preferentially retained in tumours, and with exposure to light of the correct wavelength, results in selective destruction of cancerous … Continue reading →
Oral retinoids, (Roaccutane and Neotigason), are systemic agents derived from vitamin A that are most frequently used for treating severe acne and extensive psoriasis. A review of randomised controlled trials in transplant patients who are well known to be at … Continue reading →
Topical 5-fluorouracil (5-FU) is a topical chemotherapy agent used commonly to treat precancerous lesions known as actinic or solar keratoses. With regard to the treatment of true cancers, it is only effective for the superficial type basal cell carcinomas. It … Continue reading →
Use of radiation therapy or x-ray therapy for the treatment of basal cell carcinomas in Gorlin Syndrome can lead to the development of thousands of basal cell carcinomas in the radiation field (Strong 1977; Evans, Birch et al 1991) and … Continue reading →
Micrographic (Moh’s) Surgery In 1941, Frederick Moh’s described a microscopically guided method of tracing and removing BCCs. The aim of surgery is to completely remove skin cancer by examining sections of tissue during surgery until adequate margins are achieved. It … Continue reading →
Surgical excision is a technique that involves the use of a scalpel to excise (cut out) cancerous tissue. The area of the cancer is numbed using a local anaesthetic, and a small measurement of 2-4 mm of normal skin surrounding the … Continue reading →
Laser Vaporisation is a technique involving the use of the carbon dioxide laser to vaporise away abnormal tissue after the area has been anaesthetised. It may be combined with curettage and is particularly useful in cases of multiple/superficial tumours that … Continue reading →
Cryosurgery is a term given to a procedure that involves the application of a very cold substance in order to destroy tissue. To achieve tumour killing, a tissue temperature of -50C is required. In dermatology, the most frequently used cryosurgical … Continue reading →