Diagnosis is Vital

In the past is was common for families to remain undiagnosed for several generations despite having been seen by doctors from a variety of disciplines.

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Because of the variability, presumably due to the other genes in a dosage sensitive pathway, members of a family may be affected to different degrees.

Read more: Prognosis

Diagnostic Criteria

Gorlin Syndrome is diagnosed in individuals with two major diagnostic criteria and one minor diagnostic criterion or one major and three minor diagnostic criteria.

Read more: Diagnostic Criteria

Management of Condition

Treatment is best provided by specialists with experience of the condition and should include:  

Read more: Management of Condition

Patient Dose Information Guidance

Of concern to many individuals with Gorlin Syndrome is the risk from medical diagnostic procedures. 

Read more: Patient Dose Information Guidance

 Originally produced by Professor P. A. Farndon, Clinical Geneticist, Jim Costello (deceased) and Margaret Costello.  We are reliant on a team of medical advisors for the clinical content of the website. We are grateful for their continuing support. 
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